The Chromatography process:
- Feed components have different affinities for the solid phase (resin)è different velocities / retention times across the resin bed
- Slow components have high affinity for the resin: can enter inside the resin / make complex with the resin functional groups.
- Fast components have less affinity for the resin: cannot enter inside the resin / cannot make complex with the resin functional groups.
- Primary filtration to remove mycelium
- Membrane filtration to clarify broth
- Chromatography to separate citric e.g. acid from remaining non fermented sugars, and organic and mineral impurities
- Polishing by activated carbon and ion exchange
Applications in Chemical Industries:
- Recovery of metals in liquid phases (metal plating, washing bath, metal leaching)
- Separation of metals by ion exchange
- Separation of acid/acid salts by acid retardation (sulphuric, hydrochloric, phosphoric…)
- Recovery of dyes
- Catalysis on resin
- Recycling and drying of organic solvent